Rosiglitazone (SM86-50)

Rosiglitazone is a potent and selective agonist for PPAR gamma (Peroxisome proliferator-activated receptor). PPAR gamma plays a functional role in adipogenesis, it belongs to a group of nuclear receptor proteins that are essential to the regulation of cellular differentiation, development and metabolism. It activates luciferase-based expression constructs PPAR gamma1 and PPARgamma2.