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Fibroblast Growth Factor 1 (FGF-1) is a potent inducer of DNA synthesis, cell proliferation, and has chemotactic activities. FGF-1 regulates cardiogenesis through protein kinase C signaling. FGF-1 also functions as an insulin sensitizer and mediates adipose tissue remodeling. Other homologous FGF belonging to the same family are FGF-3, FGF-5, FGF-6, K-FGF and FGF-7.
