Eotaxin-1 (GFH178-5)

Eotaxin-1, also known as Eotaxin and CCL11, is a chemokine that recruits eosinophils to sites of allergic inflammation. Eotaxin-1 signals through the G protein-coupled chemokine receptors CCR2, CCR3, and CCR5. Eotaxin-1 also negatively regulates adult neurogenesis. High Eotaxin-1 levels are associated with impaired learning and memory.