ITAC (GFH128-100)

Interferon-inducible T cell α chemoattractant (ITAC), also known as CXCL11, is expressed at high levels in leukocytes, pancreas, and liver cells. ITAC gene expression is induced by interferons α (IFN-α), β (IFN-β), and γ (IFN-γ). ITAC is the dominant ligand known to bind the chemokine receptor CXCR3, thus acting as a stronge agonist. ITAC functions as a chemoattractant for interleukin-2 (IL-2)-activated T cells.