IL-32 α (GFH151-100)

Interleukin-32 α (IL-32 α) is one of six known splice variants of the IL-32 gene. IL-32 α induces the macrophage production of inflammatory cytokines, such as interleukin-8 (IL-8), Tumor Necrosis Factor α (TNF-α), and Macrophage Inflammatory Protein 2 (MIP-2). IL-32 α expression is increased after the activation of T cells, Natural Killer (NK) cells, and interferon γ-treated epithelial cells.