Creative Biolabs

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Creative Biolabs
Antibody Discovery
Antibody Engineering

Bio-Manufacturing
Creative Biolabs台灣代理商卓昇有限公司 交貨迅速 品質有保障  電話: 02-2736 7100
Creative Biolabs 提供從基因表達或肽合成到抗體純化和標記的定制多克隆和單克隆抗體生產的全方位服務。我們有能力為診斷行業生產研究量或大規模抗體。我們進行表位預測、肽合成、蛋白質表達、多克隆或單克隆抗體生產以及從細胞培養、腹水或全血清中純化抗體。我們還通過配體親和層析製備單特異性多克隆抗體。重要的是，我們可以在 70 天內生產單克隆抗體。 Creative BioLabs 還具有處理抗原不足和針對非常不純的抗原的專業知識。
Creative Biolabs 還利用最新技術或專有協議來認證和開發可推動科學創新和標準的高質量產品。
我們始終致力於幫助客戶加快生命科學研究，解決複雜的分析難題並提高實驗室生產率。
Creative Biolabs 其中的強項是研究和臨床應用定制 mRNA 合成的領先服務提供商。
Creative Biolabs 的科學家在 mRNA 合成和修飾方面擁有超過 10 年的經驗，這使我們能夠提供具有出色純度和生物活性的定制體外轉錄 (IVT) mRNA 合成，以滿足您的項目要求。 隨著IVT方法的發展，合成mRNA已成為一類新興的基因治療。 IVT mRNA 有幾個優點，例如 mRNA 不需要核定位來介導蛋白質翻譯。蛋白質表達的細胞內過程要簡單得多，蛋白質表達水平也大大提高。 IVT mRNA 可以以 GMP 質量大規模生產，從而允許基於 mRNA 的療法的臨床應用。由於其安全性和高效性，IVT mRNA 是一種特別有吸引力的基因表達系統，可用於再生醫學、疫苗接種、細胞工程和蛋白質替代療法。
Creative Biolabs is the leading custom service provider that has extensive experience in various antibody production and engineering fields. Our service portfolio includes mouse and rat monoclonal antibody production using hybridoma technology, human, monkey, rabbit, chicken, dog, llama and camel monoclonal antibody production using various antibody library technologies (including phage display, bacterial display and yeast display). We are also professional in conducting in depth antibody humanization and affinity maturation using phage display and DNA mutagenesis approaches. In addition, OEM services for bulk scale antibody manufacturing, including bacterial production of scFv, diabody, tandem scFv, miniantibody and Fab, and mammalian cell expression of minibody, chimeric IgG and IgG, are also available at the most competitive price in the industry.
More information visit : http://www.creative-biolabs.com
 
訂購Creative Biolabs專線請洽: 卓昇有限公司 (02)2736 7100 或 0800 088 700

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Premade Antibody & Peptide Libraries

 

 

 

 

 

 

 

 

mRNA Services

 

 

 

 

 

 

Starting with a DNA template you provide, or with our gene synthesis and template construction, Creative Biolabs produces high-quality long fragments of mRNA by the IVT method for a wide range of uses, from basic research to clinical applications. Our standard process delivers high-quality material for research use, and we provide scale-up process development and custom manufacturing to meet your specific requirements for clinical use.

LibrariesLibrary IDDisplay TechnologyLibrary FormatSpeciesLibrary Size
Phage display human scFv librariesHuScL-2Phage DisplayscFvHuman1.42×109
HuScL-4Phage DisplayscFvHuman2.0×109
HuScL-6Phage DisplayscFvHuman1.0×1011
HuScL-7Phage DisplayscFvHuman1.1×1010
HuScL-2SPhage DisplayscFvHuman2.36×1010
Phage display human Fab librariesHuFabL-4Phage DisplayFabHuman1.9×1010
HuFabL-5Phage DisplayFabHuman1.1×1010
HuFabssL-1Phage DisplayFabHuman1.8×1010
Phage display mouse antibody librariesMuScL-1Phage DisplayscFvMouse8.0×108
MuScL-2Phage DisplayscFvMouse5.3×1010
MuFabL-1Phage DisplayFabMouse6.0×109
RaFabL-1Phage DisplayFabRabbit7.5×109
RaFabL-2Phage DisplayFabRabbit1.2×1010
Chicken-ScLPhage DisplayscFvChicken1.2×109
Phage display sdAb libraries (camel, llama)CaVHHL-1Phage DisplayVHHCamel1.5×109
CaVHHL-3Phage DisplayVHHCamel3.0×109
CaVHHL-4Phage DisplayVHHCamel2.63×1010
LlaVHHL-1Phage DisplayVHHLlama2.0×109
Phage display peptide librariesTriCo-16Phage DisplayPeptide (16 mer)–2.60×1010
TriCo-20Phage DisplayPeptide (20 mer)–1.70×1010
TriCo-9Phage DisplayPeptide (9 mer)–8.60×1010
TriCo-C9Phage DisplayPeptide (cyclic 9 mer)–8.60×1010

Membrane protein (Creative Biolabs)

Creative Biolabs has integrated multiple cutting-edge technologies and established a powerful Magic™ membrane protein production platform.

Cell-based Membrane Protein Expression and Purification (Creative Biolabs)

The Cell-based Membrane Protein Expression and Purification is the most commonly used approach for membrane proteins production. For membrane proteins, it can be problematic as for adequate expression levels, correct membrane insertion, and native confirmation preservation. Using our proprietary vector designs and special protocols, we have successfully generated a broad spectrum of targets.

Cell-free Membrane Protein Expression and Purification (Creative Biolabs)

Cell-free Membrane Protein Expression and Purification platform which is derived from modified cellular extracts, exert unique beneficial feature for expressing many challenging or “difficult” target, especially membrane proteins or toxic proteins. This highly robust, efficient and controllable system can also be directly reconstituted with lipids or nanodiscs, avoiding the use of detergent.

Virus Like Particles (VLPs) (Creative Biolabs)

Virus Like Particles (VLPs) are multiprotein structures that mimic the organization and conformation of authentic native viruses but lack the viral genome (non-infectious). They are widely applied in vaccinology, immunology, and virology. Currently, we offer VLP construction and purification service in various systems, including bacterial, insect, mammalian, etc. PTMs can also be incorporated.

Membrane Protein Solubilization and Stabilization (Creative Biolabs)

Most membrane proteins cannot be solubilized or stabilized in aqueous solutions without the aid of any amphipathic materials. One of the most common difficulties in handling membrane proteins is the choice of the amphipathic materials. Amphipathic materials can play an indispensable role in the extraction, solubilization, stabilization, characterization, functionalization, and activation of membrane proteins.